Collagen I rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8915
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Secreted, extracellular space, extracellular matrix .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1278
Human swiss prot no
P08123
Immunogen
Synthesized peptide derived from human Collagen I Polyclonal
Isotype
IgG
Observed band
115kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000, ELISA 1:10000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008],
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More Info
More Info
Collagen I rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
