Compstatin

Vendor: Abmole

Type: Molecular

SKU: M8983

$120.75 USD
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Coa

Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Compstatinis is a 13-residue cyclic peptide, binds to complement component C3 and inhibits complement activation with IC50 of 12 μM. Compstatin exhibits exclusive specificity for primate C3s and does not bind either to C3s from lower mammalian species or to two structural homologs of C3, human C4 and C5.
Casnumber
206645-99-0
Formula
C66H99N23O17S2
Mw
1550.77
Psmiles
CCC(C)C(N)C(=O)NC1CSSCC(NC(=O)C(CCCNC(N)=N)NC(=O)C(CC2=CN=C[NH]2)NC(=O)C(CC3=CN=C[NH]3)NC(=O)CNC(=O)C(CC4=C[NH]C5=CC=CC=C45)NC(=O)C(CC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(NC1=O)C(C)C)C(C)C)C(=O)NC(C(C)O)C(N)=O
Purity
>99%
Solubility
Water ≥ 50 mg/mL
Target synonyms
ICVVQDWGHHRCT
Compstatin

Compstatin

$120.75 USD