Crebanine

Vendor: Abmole

Type: Molecular

SKU: M19274

$235.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Crebanine, an alkaloid from Stephania venosa, induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect. Furthermore, Crebanine can inhibit the PI3K/Akt/mTOR pathway and generate reactive oxygen species, thereby blocking tumour proliferation and migration. In animal studies, Crebanine has also demonstrated central and peripheral analgesic and anti-inflammatory activity.
Casnumber
25127-29-1
Formula
C20H21NO4
Mw
339.39
Psmiles
COC1=C(OC)C2=C(C=C1)C3=C4C(C2)N(C)CCC4=CC5=C3OCO5
Purity
>99.0%
Solubility
DMSO 100 mg/mL (ultrasonic)
Crebanine

Crebanine

$235.75 USD