CRYAA rabbit pAb
Vendor: ELK Biotechnology
SKU: ES9136
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasm . Nucleus . Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1409
Human swiss prot no
P02489
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Isotype
IgG
Observed band
19kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distin
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More Info
More Info
CRYAA rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
