Crystallin-αC rabbit pAb
Vendor: ELK Biotechnology
SKU: ES20776
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.
Clonality
Polyclonal
Geneid human
26353
Human swiss prot no
Q9UJY1
Immunogen
Recombinant Protein of Crystallin-αC
Isotype
IgG
Observed band
22kD
Product weight
0.005kg
Reactivity
Human
Recommended dilutions
WB: 1:500-1000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],
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Product Citations
Product Citations
More Info
More Info
Crystallin-αC rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
