DAAM1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8614
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton, cilium basal body . Perinuclear.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
23002
Human swiss prot no
Q9Y4D1
Immunogen
Synthetic peptide from human protein at AA range: 400-500
Isotype
IgG
Observed band
123kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
WB 1:500-2000, ELISA 1:10000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct
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Product Citations
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More Info
More Info
DAAM1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
