Dalotuzumab

Vendor: Abmole

Type: Antibodies

SKU: M24531

$161.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer drugs such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.
Casnumber
1005389-60-5
Purity
>97.0%
Target synonyms
MK-0646; h7C10
Dalotuzumab

Dalotuzumab

$161.00 USD