Danicopan (ALXN2040)

Vendor: Abmole

Type: Molecular

SKU: M10145

$437.00 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Danicopan (ALXN2040, ACH-4471, ACH-0144471) is a first-in-class, potent, selective, orally active inhibitor of complement factor D with a Kd value of 0.54 nM for human Factor D. Danicopan can Selectively inhibits key complement factor D in the alternative pathway, blocking C3 convertase production and inhibiting alternative pathway activity. It also prevents the deposition of C3b fragments on blood erythrocytes and inhibits erythrocyte catabolism and extravascular hemolysis.
Casnumber
1903768-17-1
Formula
C26H23BrFN7O3
Mw
580.41
Psmiles
CC(=O)C1=N[N](CC(=O)N2CC(F)CC2C(=O)NC3=NC(=CC=C3)Br)C4=C1C=C(C=C4)C5=CN=C(C)N=C5
Purity
99.92%
Solubility
DMSO 90 mg/mL
Target synonyms
ACH-4471; ACH-0144471; ALXN2040
Danicopan (ALXN2040)

Danicopan (ALXN2040)

$437.00 USD