Deguelin

Vendor: Abmole

Type: Molecular

SKU: M6661

$115.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
Casnumber
522-17-8
Formula
C23H22O6
Mw
394.42
Psmiles
COC1=CC2=C(C=C1OC)C3C(CO2)OC4=C5C=CC(C)(C)OC5=CC=C4C3=O
Purity
>99.0%
Solubility
DMSO 60 mg/mL
Target synonyms
(-)-Deguelin; (-)-cis-Deguelin
Deguelin

Deguelin

$115.00 USD