Deucravacitinib (BMS-986165)

Vendor: Abmole

Type: Molecular

SKU: M4138

$368.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Deucravacitinib (BMS-986165) is a first-in-class, selective, orally bioavailable inhibitor of TYK2 transitions.Deucravacitinib selectively binds the TYK2 pseudokinase (JH2) structural domain with an IC50 of 1.0 nM and a Ki value of 0.02 nM. Deucravacitinib (BMS-986165) blocks receptor-mediated Tyk2 activation by stably regulating the JH2 structural domain. deucravacitinib also inhibits the IL-12/23 and type I IFN pathways. deucravacitinib may be used in psoriasis research.
Casnumber
1609392-27-9
Formula
C20H19D3N8O3
Mw
425.46
Psmiles
C(NC(=O)C1=C(NC2=CC=CC(=C2OC)C3=N[N](C)C=N3)C=C(NC(=O)C4CC4)N=N1)([2H])([2H])[2H]
Purity
99.17%
Solubility
DMSO ≥ 30 mg/mL
Target synonyms
BMS986165
Deucravacitinib (BMS-986165)

Deucravacitinib (BMS-986165)

$368.00 USD