Divarasib

Vendor: Abmole

Type: Molecular

SKU: M11442

$1,029.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Divarasib (GDC-6036) is an orally active, selective, covalently mutated KRAS G12C inhibitor with an IC50<0.01 μM for K-Ras G12C. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylated HCC1171 cells. can be used in studies related to non-small cell lung cancer ( NSCLC) related studies.
Casnumber
2417987-45-0
Formula
C29H32ClF4N7O2
Mw
622.06
Psmiles
CC1CN(CCN1C2=NC(=NC3=C(C(=C(C=C32)Cl)C4=C(C(=CC(=N4)N)C)C(F)(F)F)F)OCC5CCCN5C)C(=O)C=C
Purity
>99.0%
Solubility
DMSO 90 mg/mL
Target synonyms
GDC-6036
Divarasib

Divarasib

$1,029.25 USD