DMOG

Vendor: Abmole

Type: Molecular

SKU: M2558

$115.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
DMOG (Dimethyloxaloyl glycine) is an antagonist of α-ketoglutarate cofactor and a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.
Casnumber
89464-63-1
Formula
C6H9NO5
Mw
175.14
Psmiles
COC(=O)CNC(=O)C(=O)OC
Purity
99.53%
Solubility
DMSO ≥ 70 mg/mL; Water 40 mg/mL
Target synonyms
Dimethyloxallyl Glycine
DMOG

DMOG

$115.00 USD