E2F-1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8529
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IF;WB;IHC;ELISA
Cellular localization
Nucleus .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1869
Human swiss prot no
Q01094
Immunogen
Synthetic peptide from human protein at AA range: 100-170
Isotype
IgG
Observed band
60kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
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More Info
More Info
E2F-1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
