E6446

Vendor: Abmole

Type: Molecular

SKU: M11308

$345.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interactions in vitro. E6446 is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling.
Casnumber
1219925-73-1
Formula
C27H35N3O3
Mw
449.59
Psmiles
C1CCN(C1)CCCOC2=CC=C(C=C2)C3=NC4=C(O3)C=C(C=C4)OCCCN5CCCC5
Purity
>98.0%
Solubility
DMSO 5 mg/mL; Ethanol 45 mg/mL
Target synonyms
E-6446
E6446

E6446

$345.00 USD