E6446 dihydrochloride

Vendor: Abmole

Type: Molecular

SKU: M9289

$284.05 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
E6446 dihydrochloride is a potent and orally acitve antagonist of TLR7 and TLR9. E6446 dihydrochloride is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling.
Casnumber
1345675-25-3
Formula
C27H37Cl2N3O3
Mw
522.51
Psmiles
Cl.Cl.C1CCN(C1)CCCOC2=CC=C(C=C2)C3=NC4=C(O3)C=C(OCCCN5CCCC5)C=C4
Purity
>99%
Solubility
DMSO 5.2 mg/mL (Need ultrasonic and warming)
Target synonyms
E6446 2HCl; E-6446 hydrochloride
E6446 dihydrochloride

E6446 dihydrochloride

$284.05 USD