EAI045

Vendor: Abmole

Type: Molecular

SKU: M6081

$281.75 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
EAI045 is a fourth generation allosteric inhibitor of mutant EGFR, which inhibits EGFR at 10 μM ATP, EGFRL858R, EGFRT790M and EGFRL858R/T790M with IC50 values of 1.9, 0.019, 0.19 and 0.002 μM respectively.
Casnumber
1942114-09-1
Formula
C19H14FN3O3S
Mw
383.40
Psmiles
OC1=CC=C(F)C=C1C(N2CC3=C(C=CC=C3)C2=O)C(=O)NC4=NC=CS4
Purity
>98%
Solubility
76 mg/mL in DMSO
EAI045

EAI045

$281.75 USD