eIF2α (phospho Ser51) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1304
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IF;WB;IHC;ELISA
Cellular localization
Cytoplasm, Stress granule . Colocalizes with NANOS3 in the stress granules. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1965
Human swiss prot no
P05198
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Ser51. AA range:21-70
Isotype
IgG
Observed band
38kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat;Dog;Pig;Fish
Recommended dilutions
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],
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Product Citations
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More Info
More Info
eIF2α (phospho Ser51) rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
