ELNE rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10882
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasmic vesicle, phagosome . Localized in phagolysosomes following ingestion of E.coli by neutrophils. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1991
Human swiss prot no
P08246
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
29kD
Product weight
0.005kg
Reactivity
Human;Mouse;Bovine;Bovine
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016
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More Info
More Info
ELNE rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
