Epoxomicin

Vendor: Abmole

Type: Molecular

SKU: M2193

$572.70 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Epoxomicin (BU-4061T) is a cell-permeable, selective and irreversible proteasome inhibitor with an IC50 value of 4 nM. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier.
Casnumber
134381-21-8
Formula
C28H50N4O7
Mw
554.72
Psmiles
CCC(C)C(NC(=O)C(C(C)CC)N(C)C(C)=O)C(=O)NC(=O)C(NC(CC(C)C)C(=O)C1(C)CO1)C(C)O
Purity
>99.0%
Solubility
DMSO 80 mg/mL
Target synonyms
BU 4061T
Epoxomicin

Epoxomicin

$572.70 USD