F-1

Vendor: Abmole

Type: Molecular

SKU: M58399

$437.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50 values of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively.
Casnumber
2244775-31-1
Formula
C22H27ClN8O3S
Mw
519.02
Psmiles
CN1CCN(CC1)C2=NC(=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl)OC
Purity
≥98.0%
Solubility
DMSO 65 mg/mL
F-1

F-1

$437.00 USD