FBN1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES5222
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Secreted . Fibrillin-1 and Asprosin chains are still linked together during the secretion from cells, but are subsequently separated by furin (PubMed:24982166). .; [Fibrillin-1]: Secreted, extracellular space, extracellular matrix .; [Asprosin]: Secreted . Secreted by white adipose tissue and circulates in the plasma. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2200
Human swiss prot no
P35555
Immunogen
The antiserum was produced against synthesized peptide derived from human Fibrillin-1. AA range:2811-2860
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016],
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More Info
More Info
FBN1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
