Fedratinib hydrochloride hydrate

Vendor: Abmole

Type: Molecular

SKU: M28279

$166.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively.
Casnumber
1374744-69-0
Formula
C27H40Cl2N6O4S
Mw
615.62
Psmiles
CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4.O.Cl.Cl
Purity
≥99.0%
Solubility
DMSO 100 mg/mL (ultrasonic); Water 100 mg/mL (ultrasonic)
Target synonyms
TG-101348 hydrochloride hydrate; SAR 302503 hydrochloride hydrate
Fedratinib hydrochloride hydrate

Fedratinib hydrochloride hydrate

$166.75 USD