FILA rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11828
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF
Cellular localization
Cytoplasmic granule . In the stratum granulosum of the epidermis, localized within keratohyalin granules (PubMed:1429717). In granular keratinocytes and in lower corneocytes, colocalizes with calpain-1/CAPN1 (PubMed:21531719). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2312
Human swiss prot no
P20930
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
446kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009],
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More Info
FILA rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
