FKB1A rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11839
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cytoplasm, cytosol . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2280
Human swiss prot no
P62942
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Isotype
IgG
Observed band
11kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided b
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More Info
More Info
FKB1A rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

