Flavopiridol hydrochloride

Vendor: Abmole

Type: Molecular

SKU: M3483

$86.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA.
Casnumber
131740-09-5
Formula
C21H20ClNO5.HCl
Mw
438.3
Psmiles
Cl.CN1CCC(C(O)C1)C2=C3OC(=CC(=O)C3=C(O)C=C2O)C4=C(Cl)C=CC=C4
Purity
>99.0%
Solubility
Water 20 mg/mL; DMSO 22 mg/mL
Target synonyms
NSC 649890 HCl; Alvocidib hydrochloride; L86 8275 HCl; HMR-1275 HCl
Flavopiridol hydrochloride

Flavopiridol hydrochloride

$86.25 USD