Flk-1/VEGFR2 (phospho Tyr1059) rabbit pAb

Flk-1/VEGFR2 (phospho Tyr1059) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES6016

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;ELISA
Cellular localization
Cell junction . Endoplasmic reticulum . Cell membrane . Localized with RAP1A at cell-cell junctions (By similarity). Colocalizes with ERN1 and XBP1 in the endoplasmic reticulum in endothelial cells in a vascular endothelial growth factor (VEGF)-dependent manner (PubMed:23529610). .; [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Detected on caveolae-enriched lipid rafts at the cell surface. Is recycled from the plasma membrane to endosomes and back again. Phosphorylation triggered by VEGFA binding promotes internalization and subsequent degradation. VEGFA binding triggers internalization and translocation to the nucleus.; [Isoform 2]: Secreted .; [Isoform 3]: Secreted.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3791
Human swiss prot no
P35968
Immunogen
The antiserum was produced against synthesized peptide derived from human VEGFR2 around the phosphorylation site of Tyr1059. AA range:1025-1074
Isotype
IgG
Observed band
170kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Flk-1/VEGFR2 (phospho Tyr1059) rabbit pAb

Flk-1/VEGFR2 (phospho Tyr1059) rabbit pAb

$148.00 USD