Fluzoparib (SHR3162)

Vendor: Abmole

Type: Molecular

SKU: M10445

$304.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Fluzoparib (SHR3162) is an effective oral active PARP1 inhibitor (IC50=1.46±0.72 nM) with superior antitumor activity. Fluzoparib selectively inhibited the proliferation of homologous recombination repair (HR) deficient cells and sensitized HR deficient cells to cytotoxic drugs. Fluzoparib has good pharmacokinetic properties in vivo and can be used in cancer research.
Casnumber
1358715-18-0
Formula
C22H16F4N6O2
Mw
472.40
Psmiles
FC1=CC=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1C(=O)N4CC[N]5N=C(N=C5C4)C(F)(F)F
Purity
>98.5%
Solubility
DMSO 35 mg/mL
Target synonyms
SHR3162; Fuzuopali; Fuzuloparibum
Fluzoparib (SHR3162)

Fluzoparib (SHR3162)

$304.75 USD