Erythromycin

Erythromycin is a macrolide antibioticum with a bacteriostatic action against primarily gram-positive bacteria. The antibiotic binds reversibly to the 50S subunit of the bacterial ribosome, resulting in inhibition of both transpeptidation and translocation reactions, inhibition of protein synthesis and hence inhibition of cell growth. Specifications   Physical description White or pale yellow powder Identification According to BP Specific optical rotation -71 to -78 o Related substances Any individual impurity: <= 3.0% Total Impurities: <= 7.0% Thiocyanate <= 0.3% Water <= 6.5% Sulphated Ash <= 0.2% Assay Erythromycin A+B+C: 93.0 – 102.0% Erythromycin B: <= 5.0% Erythromycin C: <-5.0% Pharmacopoeia Specification(s) BP Store dry at 4-8°C  CAS 114-07-8