FoxO3a (phospho-Ser7) rabbit pAb
Vendor: ELK Biotechnology
SKU: ES16335
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Cytoplasm, cytosol . Nucleus . Mitochondrion matrix . Mitochondrion outer membrane ; Peripheral membrane protein ; Cytoplasmic side . Retention in the cytoplasm contributes to its inactivation (PubMed:10102273, PubMed:15084260, PubMed:16751106). Translocates to the nucleus upon oxidative stress and in the absence of survival factors (PubMed:10102273, PubMed:16751106). Translocates from the cytosol to the nucleus following dephosphorylation in response to autophagy-inducing stimuli (By similarity). Translocates in a AMPK-dependent manner into the mitochondrion in response to metabolic stress (PubMed:23283301, PubMed:29445193). Serum deprivation increases localization to the nucleus, leading to activate expression of SOX9 and subsequent chondrogenesis (By similarity). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2309
Human swiss prot no
O43524
Immunogen
Synthesized phosho peptide around human FoxO3a (Ser7)
Isotype
IgG
Observed band
90kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:1000-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008],
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Product Citations
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More Info
More Info
FoxO3a (phospho-Ser7) rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

