Frizzled-7 rabbit pAb

Name: Frizzled-7 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES2373

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;Flow Cyt;IF;ELISA

Cellular localization

Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2). Localized in recycling endosomes in other conditions. .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

8324

Human swiss prot no

O75084

Immunogen

The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94

Isotype

IgG

Observed band

64kD

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

WB 1:500-2000;Flow Cyt 1:50-200;IF/ICC 1:100-500;ELISA 1:5000-20000

Source

Rabbit

Storage

-20°C/1 year

Background

frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],

Frizzled-7 rabbit pAb

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