Futibatinib (TAS-120)

Vendor: Abmole

Type: Molecular

SKU: M10026

$241.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Futibatinib (TAS-120) is an oral bioavailable, highly selective and irreversible FGFR inhibitor with IC50 of 3.9, 1.3, 1.6 and 8.3 nM against the four FGFR 1-4 subtypes, respectively. Futibatinib inhibited mutant and wild-type FGFR2 with IC50 similarity (wild-type FGFR2=0.9 nM; V5651 = 1 to 3 nM; N550H = 3.6 nM. E566G = 2.4 nM).
Casnumber
1448169-71-8
Formula
C22H22N6O3
Mw
418.45
Psmiles
COC1=CC(=CC(=C1)C#CC2=N[N](C3CCN(C3)C(=O)C=C)C4=NC=NC(=C24)N)OC
Purity
99.94%
Solubility
DMSO ≥ 60 mg/mL
Target synonyms
TAS-120
Futibatinib (TAS-120)

Futibatinib (TAS-120)

$241.50 USD