G140

Vendor: Abmole

Type: Molecular

SKU: M29550

$483.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity.
Casnumber
2369751-07-3
Formula
C17H16Cl2N4O2
Mw
379.24
Psmiles
C[N]1C=CC(=N1)C2=C3C4=C(CCN(C4)C(=O)CO)[NH]C3=C(Cl)C(=C2)Cl
Purity
≥99.0%
Solubility
DMSO 250 mg/mL (ultrasonic)
G140

G140

$483.00 USD