G5-7

Vendor: Abmole

Type: Molecular

SKU: M31205

$333.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
G5-7 is an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5-7 has the potential for glioma study.
Casnumber
939681-36-4
Formula
C22H19F2NO3
Mw
383.39
Psmiles
CCOC(=O)N1CC(=C/C2=CC=CC=C2F)/C(=O)C(/C1)=C\C3=CC=CC=C3F
Purity
≥99.0%
Solubility
DMSO ≥60 mg/mL (Need ultrasonic)
G5-7

G5-7

$333.50 USD