GABA B Receptor 2 Rabbit pAb
Vendor: ELK Biotechnology
SKU: ES20746
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
IHC;IF
Cellular localization
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
9568
Human swiss prot no
O75899
Immunogen
Synthetic Peptide of GABA B Receptor 2 AA range: 785-835
Isotype
IgG
Observed band
106kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
IHC 1:100-200
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010],
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More Info
More Info
GABA B Receptor 2 Rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
