GB1107

Vendor: Abmole

Type: Molecular

SKU: M9897

$540.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GB1107 is a potent, selective, orally active galectin-3 inhibitor with Kd of 37 nM. GB1107 inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade. GB1107 potentiates the effects of a PD-L1 immune checkpoint inhibitor to increase expression of cytotoxic (IFN-γ, granzyme B, perforin-1, Fas ligand) and apoptotic (cleaved caspase-3) effector molecules.
Casnumber
1978336-61-6
Formula
C20H16Cl2F3N3O4S
Mw
522.32
Psmiles
OCC1OC(SC2=CC=C(Cl)C(=C2)Cl)C(O)C(C1O)[N]3C=C(N=N3)C4=CC(=C(F)C(=C4)F)F
Purity
>99.0%
Solubility
DMSO 45 mg/mL
Target synonyms
GB-1107
GB1107

GB1107

$540.50 USD