GDC-0623

Vendor: Abmole

Type: Molecular

SKU: M14169

$287.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM).
Casnumber
1168091-68-6
Mw
456.21
Psmiles
OCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)[N]3C=NC=C3C=C1
Purity
>99%
Solubility
DMSO 50 mg/mL
Target synonyms
RG 7421; MEK inhibitor 1
GDC-0623

GDC-0623

$287.50 USD