Gefitinib

Vendor: Abmole

Type: Molecular

SKU: M1749

$46.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Gefitinib (ZD1839) is an EGFR tyrosine kinase and Akt phosphorylation inhibitor. Gefitinib significantly down-regulates CD47 expression and increases DC phagocytosis in non-small cell lung cancer cells such as PC9, H1437 and H1573. Gefitinib combined with CD47 antibody can enhance the phagocytosis of macrophages.
Casnumber
184475-35-2
Formula
C22H24ClFN4O3
Mw
446.90
Psmiles
COC1=C(OCCCN2CCOCC2)C=C3C(=NC=NC3=C1)NC4=CC=C(F)C(=C4)Cl
Purity
99.97%
Solubility
DMSO 68 mg/mL
Target synonyms
ZD-1839, Iressa
Gefitinib

Gefitinib

$46.00 USD