GFB-8438

Vendor: Abmole

Type: Molecular

SKU: M10927

$207.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GFB-8438 is a potent subtype selective TRPC5 inhibitor against hTRPC5 and hTRPC4 IC50 0.18 and 0.29 μM, respectively. GFB-8438 has good selectivity for TRPC6, other members of the TRP family, NaV1.5, and limited activity against hERG channels. Protective effect of GFB-8438 on mouse podocytes.
Casnumber
2304549-73-1
Formula
C16H14ClF3N4O2
Mw
386.76
Psmiles
FC(F)(F)C1=CC=CC=C1CN2CCN(CC2=O)C3=C(Cl)C(=O)NN=C3
Purity
99.61%
Solubility
DMSO ≥ 60 mg/mL
GFB-8438

GFB-8438

$207.00 USD