Glut4 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4253
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Multi-pass membrane protein . Endomembrane system ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized (PubMed:8300557). The dileucine internalization motif is critical for intracellular sequestration (PubMed:8300557). Insulin stimulation induces translocation to the cell membrane (By similarity). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6517
Human swiss prot no
P14672
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A4. AA range:21-70
Isotype
IgG
Observed band
56kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008],
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Product Citations
Product Citations
More Info
More Info
Glut4 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

