GMB-475

Vendor: Abmole

Type: Molecular

SKU: M21032

$230.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.
Casnumber
2490599-18-1
Formula
C43H46F3N7O7S
Mw
861.93
Psmiles
CC1=C(SC=N1)C2=CC=C(CNC(=O)C3CC(O)CN3C(=O)C(NC(=O)COCCOC4=CC=C(C=C4)C5=CC(=NC=N5)NC6=CC=C(OC(F)(F)F)C=C6)C(C)(C)C)C=C2
Purity
>98.5%
Solubility
DMSO 100 mg/mL
GMB-475

GMB-475

$230.00 USD