GSK046

Vendor: Abmole

Type: Molecular

SKU: M10759

$552.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GSK046 (iBET-BD2) is an effective, selective and orally active inhibitor of the BD2 bromine domain of the BET protein,IC50 The values are 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2), and 214 nM (BRDT BD2). GSK046 has immunomodulatory activity.
Casnumber
2474876-09-8
Formula
C23H27FN2O4
Mw
414.47
Psmiles
CC(OC1=CC(=CC(=C1NC(C)=O)F)C(=O)NC2CCC(O)CC2)C3=CC=CC=C3
Purity
>99.0%
Solubility
DMSO ≥ 60 mg/mL
Target synonyms
iBET-BD2
GSK046

GSK046

$552.00 USD