GSK1120212 (Trametinib)

Vendor: Abmole

Type: Molecular

SKU: M1759

$126.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Trametinib (GSK1120212; Jtp-74057) is an orally effective MEK inhibitor with IC50 of 2 nM against MEK1 and MEK2, respectively. Trametinib can activate autophagy and induce apoptosis.
Casnumber
871700-17-3
Formula
C26H23FIN5O4
Mw
615.39
Psmiles
CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=CC=C(I)C=C4F)C5=CC(=CC=C5)NC(C)=O)C
Purity
99.81%
Solubility
DMSO 30 mg/mL
Target synonyms
JTP-74057, GSK212
GSK1120212 (Trametinib)

GSK1120212 (Trametinib)

$126.50 USD