GSK180736A

Vendor: Abmole

Type: Molecular

SKU: M5269

$862.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GSK180736A, developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1); ≥400-fold selective for GRK2 over both GRK1 and GRK5.
Casnumber
817194-38-0
Formula
C19H16FN5O2
Mw
365.36
Psmiles
CC1=C(C(NC(=O)N1)C2=CC=C(F)C=C2)C(=O)NC3=CC4=C([NH]N=C4)C=C3
Purity
>98.0%
Solubility
73 mg/mL in DMSO
Target synonyms
GSK180736
GSK180736A

GSK180736A

$862.50 USD