תמונת ברירת מחדל

GSK5182

Vendor: Abmole

Type: Molecular

SKU: M20777

$212.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GSK5182 is a 4-Hydroxytamoxifen analog and a highly potent, selective, orally active estrogen-related receptor gamma (ERRγ) inverse agonist with an IC50 value of 79 nM.GSK5182 does not interact with other nuclear receptors, including ERRα and ERα. In addition, GSK5182 inhibits proinflammatory cytokine-induced catabolic factors and increases ROS production in liver cancer cells. cytokine-induced catabolic factors and increased ROS production in hepatocellular carcinoma cells.
Casnumber
877387-37-6
Formula
C27H31NO3
Mw
417.54
Psmiles
CN(C)CCOC1=CC=C(C=C1)/C(=C(/CCCO)C2=CC=CC=C2)C3=CC=C(O)C=C3
Purity
>99%
Solubility
DMSO 84 mg/mL
תמונת ברירת מחדל

GSK5182

$212.75 USD