GW4869 2HCl

Vendor: Abmole

Type: Molecular

SKU: M4974

$189.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
GW4869 (GW69A, GW554869A) is a noncompetitive inhibitor of neutral Smase (spspingolipase) with IC50 of 1 μM. GW4869 is also an inhibitor of exosome biogenesis/release, followed by endotoxin (LPS) challenge. GW4869 could effectively inhibit the generation of exosomes in macrophages and in vivo.
Casnumber
6823-69-4
Formula
C30H30Cl2N6O2
Mw
577.50
Psmiles
C1CN=C(N1)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(C=C3)C=CC(=O)NC4=CC=C(C=C4)C5=NCCN5.Cl.ClC1CN=C(N1)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(C=C3)C=CC(=O)NC4=CC=C(C=C4)C5=NCCN5.O.Cl.ClC1CN=C(N1)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(C=C3)C=CC(=O)NC4=CC=C(C=C4)C5=NCCN5
Purity
99.87%
Solubility
DMSO 1 mg/mL (Need ultrasonic)
Target synonyms
GW69A; GW554869A
GW4869 2HCl

GW4869 2HCl

$189.75 USD