Histone H2B rabbit pAb
Vendor: ELK Biotechnology
SKU: ES2527
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus. Chromosome.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
54145
Human swiss prot no
P57053
Immunogen
The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:10-59
Isotype
IgG
Observed band
14kD
Product weight
0.005kg
Reactivity
Human;Mouse;Monkey
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
H2BFS is a Pseudogene. Histone H2B type 1-H is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. Diseases associated with H2BFS include endometrial stromal sarcoma. Among its related pathways are Packaging Of Telomere Ends. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BH.
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Product Citations
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More Info
More Info
Histone H2B rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
