HMG-1 (Acetyl Lys12) rabbit pAb

HMG-1 (Acetyl Lys12) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES1135

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus . Chromosome . Cytoplasm . Secreted . Cell membrane ; Peripheral membrane protein ; Extracellular side . Endosome . Endoplasmic reticulum-Golgi intermediate compartment . In basal state predominantly nuclear. Shuttles between the cytoplasm and the nucleus (PubMed:12231511, PubMed:17114460). Translocates from the nucleus to the cytoplasm upon autophagy stimulation (PubMed:20819940). Release from macrophages in the extracellular milieu requires the activation of NLRC4 or NLRP3 inflammasomes (By similarity). Passively released to the extracellular milieu from necrotic cells by diffusion, involving the fully reduced HGMB1 which subsequently gets oxidized (PubMed:19811284). Also released from apoptotic cells (PubMed:16855214, PubMed:18631454). Active secretion from a variety of immune a
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
3146
Human swiss prot no
P09429
Immunogen
Synthesized acetyl-peptide derived from the N-terminal region of human HMG-1 around the acetylation site of K12.
Isotype
IgG
Observed band
about 30kd
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
HMG-1 (Acetyl Lys12) rabbit pAb

HMG-1 (Acetyl Lys12) rabbit pAb

$148.00 USD