HPA1 rabbit pAb

HPA1 rabbit pAb

Vendor: ELK Biotechnology

SKU: ES4083

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;IHC;IF;ELISA
Cellular localization
Lysosome membrane; Peripheral membrane protein. Secreted. Nucleus. Proheparanase is secreted via vesicles of the Golgi. Interacts with cell membrane heparan sulfate proteoglycans (HSPGs). Endocytosed and accumulates in endosomes. Transferred to lysosomes where it is proteolytically cleaved to produce the active enzyme. Under certain stimuli, transferred to the cell surface. Associates with lipid rafts. Colocalizes with SDC1 in endosomal/lysosomal vesicles. Accumulates in perinuclear lysosomal vesicles. Heparin retains proheparanase in the extracellular medium (By similarity). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
10855
Human swiss prot no
Q9Y251
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human HPSE. AA range:241-290
Isotype
IgG
Observed band
62kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
HPA1 rabbit pAb

HPA1 rabbit pAb

$148.00 USD