IACS-13909

Vendor: Abmole

Type: Molecular

SKU: M10738

$460.00 USD
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Product Overview

Bioactivity
IACS-13909 is a potent selective, orally active SHP2 allosteric inhibitor IC50 for 15.7 nM,Kd 32 nM. IACS-13909 is more selective for SHP2 than other phosphatase, including SHP1. IACS-13909 inhibits the signaling of the receptor tyrosine kinase (RTK)/MAPK pathway and has an anticancer effect.
Casnumber
2160546-07-4
Formula
C17H18Cl2N6
Mw
377.27
Psmiles
CC1(N)CCN(CC1)C2=CN=C3C(=N2)[NH]N=C3C4=CC=CC(=C4Cl)Cl
Purity
>99.0%
Solubility
DMSO ≥ 10 mg/mL
IACS-13909

IACS-13909

$460.00 USD