Iberdomide

Vendor: Abmole

Type: Molecular

SKU: M6072

$212.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Iberdomide (CC-220) is an orally effective cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 for cereblon binding affinity of approximately 150 nM. Iberdomide (CC-220) binds CRBN with higher affinity than lenalidomide and pomalidomide and has enhanced degradation of IKZF1 and IKZF3 with enhanced degradation.
Casnumber
1323403-33-3
Formula
C25H27N3O5
Mw
449.5
Psmiles
O=C1CCC(N2CC3=C(OCC4=CC=C(CN5CCOCC5)C=C4)C=CC=C3C2=O)C(=O)N1
Purity
>99.0%
Solubility
DMSO >100 mg/mL
Target synonyms
CC220; CC 220; CC-220
Iberdomide

Iberdomide

$212.75 USD